If You Have O+ Blood, Your Ancestors Weren't Human

 Two children arrive at the same hospital with the same deadly malaria. One is far

more likely to survive — and in 2007, researchers finally proved why. It wasn't the treatment. It was blood type.

https://youtu.be/hLQbLzoKXOQ This is the honest story of Type O blood — not the horoscope, not the diet, not the "you're special" version. The truth is stranger. The most common blood type on Earth is, at the level of your DNA, a broken gene — a copy of an older gene that failed, and kept failing, in population after population, for tens of thousands of years. And it kept winning anyway, because in a world full of plagues, that broken gene was worth having. Inside: why group O is 66% less likely to suffer severe malaria (and the elegant mechanism behind it), why the very same blood pays for that protection when cholera reaches a river delta, what a stomach bacterium built a docking protein to grab, and the honest other side of the ledger — the clots and cancers Type O is actually protected from. Plus the correction almost nobody makes: the Black Death was never a blood-type event at all — and the study that made headlines about it is still being argued over by the scientists who ran it. Your blood type was never a personality. It's a record — of exactly which diseases your bloodline survived, written before anyone could read it. ⏱ We dig into the mysteries history tried to bury. And we don't make them up. 🔔 Subscribe to Stone & Bone — we take the version everyone believes and go find out what the DNA actually says, including where the scientists disagree. SOURCES & FURTHER READING : - ▶Rowe JA et al. — Blood group O protects against severe P. falciparum malaria through reduced rosetting. PNAS 2007 ▶ Ségurel L et al. — The ABO blood group is a trans-species polymorphism in primates. PNAS 2012 ▶ Harris JB et al. — Blood group, immunity, and risk of infection with Vibrio cholerae. Infection & Immunity 2005 ▶ Glass RI et al. — Predisposition for cholera of individuals with O blood group. Am J Epidemiology 1985 ▶ Borén T et al. — H. pylori attachment mediated by blood group antigens (BabA–Lewis b). Science 1993 ▶ Wolpin BM et al. — ABO blood group and risk of pancreatic cancer. JNCI 2009 ▶ Klunk J et al. — Evolution of immune genes is associated with the Black Death (ERAP2). Nature 2022 ▶ Barton AR, Santander CG et al. — Insufficient evidence for natural selection associated with the Black Death. Nature 2024 #TypeOBlood #BloodType #DNA #Genetics #Malaria #HiddenHistory #Ancestry #StoneAndBone BS202AR — Some scenes are dramatized reconstructions based on published research. Effect sizes are quoted from the peer-reviewed studies named above; where a finding is a hypothesis or is contested, we say so on screen. Stone & Bone does not fabricate evidence. This video is history and science, not medical advice.